|本期目录/Table of Contents|

[1]王伟,张利雄.药物连续制备的研究进展[J].南京工业大学学报(自然科学版),2019,41(02):252-260.[doi:10.3969/j.issn.1671-7627.2019.02.019]
 WANG Wei,ZHANG Lixiong.Recent advance on continuous manufacture of pharmaceutical materials[J].Journal of NANJING TECH UNIVERSITY(NATURAL SCIENCE EDITION),2019,41(02):252-260.[doi:10.3969/j.issn.1671-7627.2019.02.019]
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药物连续制备的研究进展()
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《南京工业大学学报(自然科学版)》[ISSN:1671-7627/CN:32-1670/N]

卷:
41
期数:
2019年02期
页码:
252-260
栏目:
出版日期:
2019-03-19

文章信息/Info

Title:
Recent advance on continuous manufacture of pharmaceutical materials
文章编号:
1671-7627(2019)02-0252-09
作者:
王伟张利雄
南京工业大学 化工学院 材料化学工程国家重点实验室,江苏 南京 210009
Author(s):
WANG WeiZHANG Lixiong
State Key Laboratory of Materials-Oriented Chemical Engineering,College of Chemical Engineering,Nanjing Tech University,Nanjing 210009,China
关键词:
微反应器 药物合成 流体化学
Keywords:
microreactor pharmaceutical synthesis flow Chemistry
分类号:
O621.1
DOI:
10.3969/j.issn.1671-7627.2019.02.019
文献标志码:
A
摘要:
药物的连续制备具有安全、高效、节约、绿色等优点,近年来已经报道了大量药物连续合成的成功案例,引起了学术界和工业界的广泛关注。本文对这些案例进行综述,详细介绍药物连续制备中的均相反应、多相催化反应、光反应、气体参与的反应以及进行连续在线纯化和制剂方面的技术,分析该技术的优势,对今后发展进行展望。
Abstract:
The continuous manufacture of pharmaceutical materials has the advantages of safety,efficiency,economy,greenness and so on,thus attracting a great attention.In recent years,a large number of technologies for continuous manufacture of pharmaceutical materials have been successfully developed,which has aroused widespread concern academically and industrially.In this review,the emphasis was put on the homogeneous reaction,catalytic reactions,the photo-induced reactions,the reactions involving gases as well as the continuous in-line purification and formulation of pharmacy.The advantages of using such technologies were discussed,and the future research direction was envisioned.

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备注/Memo

备注/Memo:
收稿日期:2017-06-07
作者简介:王伟(1989—),男,E-mail:306129770@qq.com; 张利雄(联系人),教授,E-mail:lixzhang@njtech.edu.cn.
引用本文:王伟,张利雄.药物连续制备的研究进展[J].南京工业大学学报(自然科学版),2019,41(2):252-260..
更新日期/Last Update: 2019-03-31